Publications
2024
Dbf4-depedent kinase finetunes INO80 function at chromosome replication origins.
Bansal P, Lahiri S, Kumar C, Chacin E., Ortiz-Bazan MA, Mueller M, Vizjak P, Straub T, Mueller-Planitz F, Aguilera A, Gomez-Gonzalez B, Pfander B, Imhof A*, and Kurat CF* (2024). bioRxiv, doi: 10.1101/2023.06.10.598178. * Corresponding authors Link.
The budding yeast Fkh1 Forkhead associated (FHA) domain promotes the G1-chromatin status and activity of chromosomal DNA replication origins.
Hoggard, T, Chacin, E, Hollatz, AJ, Kurat, CF & Fox, CA (2024). bioRxiv, doi:10.1101/2024.02.16.580712. Link.
2023
Establishment and function of chromatin organization at replication origins
Chacin E, Reusswig KU, Furtmeier J, Bansal P, Karl LA, Pfander B, Straub T, Korber P, Kurat CF. Nature. 2023 Apr;616(7958):836-842. doi: 10.1038/s41586-023-05926-8. Epub 2023 Apr 5. PMID: 37020028. Link.
DNA mimic foldamers affect chromatin composition and disturb cell cycle progression
Kleene V, Corvaglia V, Chacin E, Forne I, Konrad DB, Khosravani P, Douat C, Kurat CF, Huc I, Imhof A. Nucleic Acids Res. 2023 Aug 31:gkad681. doi: 10.1093/nar/gkad681. Epub ahead of print. PMID: 37650653. Link.
A SAM-key domain required for enzymatic activity of the Fun30 nucleosome remodeler
Karl LA, Galanti L, Bantele SC, Metzner F, Šafarić B, Rajappa L, Foster B, Pires VB, Bansal P, Chacin E, Basquin J, Duderstadt KE, Kurat CF, Bartke T, Hopfner KP, Pfander B. Life Sci Alliance. 2023 Jul 19;6(9):e202201790. doi: 10.26508/lsa.202201790. PMID: 37468166; PMCID: PMC10355287. Link
2022
Yta7, a chromatin segregase regulated by the cell cycle machinery
Bansal P, Kurat CF. Mol Cell Oncol. 2022 Mar 17;9(1):2039577. doi: 10.1080/23723556.2022.2039577. PMID: 35308047; PMCID: PMC8932914. Link.
The fork protection complex recruits FACT to reorganize nucleosomes during replication
Safaric B, Chacin E, Scherr MJ, Rajappa L, Gebhardt C, Kurat CF, Cordes T, Duderstadt KE. Nucleic Acids Res. 2022 Feb 22;50(3):1317-1334. doi: 10.1093/nar/gkac005. PMID: 35061899; PMCID: PMC8860610.
2021
A CDK-regulated chromatin segregase promoting chromosome replication
Chacin E, Bansal P, Reusswig KU, Diaz-Santin LM, Ortega P, Vizjak P, Gómez-González B, Müller-Planitz F, Aguilera A, Pfander B, Cheung ACM, Kurat CF. Nat Commun. 2021 Sep 1;12(1):5224. doi: 10.1038/s41467-021-25424-7. PMID: 34471130; PMCID: PMC8410769.
Editorial: The Evolving Chromatin and Transcriptional Landscapes-Emerging Methods, Tools and Techniques
Bilodeau S, Kurat CF, Lambert JP. Front Cell Dev Biol. 2021 Nov 1;9:782776. doi: 10.3389/fcell.2021.782776. PMID: 34790670; PMCID: PMC8591211.
2020
Chromatin Fiber Invasion and Nucleosome Displacement by the Rap1 Transcription Factor
Mivelaz M, Cao AM, Kubik S, Zencir S, Hovius R, Boichenko I, Stachowicz AM, Kurat CF, Shore D, Fierz B. Mol Cell. 2020 Feb 6;77(3):488-500.e9. doi: 10.1016/j.molcel.2019.10.025. Epub 2019 Nov 21. PMID: 31761495; PMCID: PMC7005674.
2018
Functional Analysis of Hif1 Histone Chaperone in Saccharomyces cerevisiae
Dannah NS, Nabeel-Shah S, Kurat CF, Sabatinos SA, Fillingham J. G3 (Bethesda). 2018 May 31;8(6):1993-2006. doi: 10.1534/g3.118.200229. PMID: 29661843; PMCID: PMC5982827.
2017
Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates
Kurat CF, Yeeles JTP, Patel H, Early A, Diffley JFX. . Mol Cell. 2017 Jan 5;65(1):117-130. doi: 10.1016/j.molcel.2016.11.016. Epub 2016 Dec 15. PMID: 27989438; PMCID: PMC5222724.
A global genetic interaction network maps a wiring diagram of cellular function
Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, Lin ZY, Kuzmin E, Nelson J, Piotrowski JS, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat CF, Li SC, Li Z, Usaj MM, Okada H, Pascoe N, San Luis BJ, Sharifpoor S, Shuteriqi E, Simpkins SW, Snider J, Suresh HG, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya OG, Stagljar I, Xia T, Ohya Y, Gingras AC, Raught B, Boutros M, Steinmetz LM, Moore CL, Rosebrock AP, Caudy AA, Myers CL, Andrews B, Boone C. Science. 2016 Sep 23;353(6306):aaf1420. doi: 10.1126/science.aaf1420. PMID: 27708008; PMCID: PMC5661885.